September 22, 2014

Testosterone Replacement Therapy and Anti-Doping Tests

Ask Bill Roberts: MMA fighter Chael Sonnen failed two anti-doping tests which revealed that he used exogenous testosterone. At his recent hearing, his defense was that he was on testosterone replacement therapy (TRT). My question is, how would TRT effect the T/E ratio? Does exogenous testosterone also shutdown epitestosterone production creating a scenario where someone can have a high ratio due to exogenous test, and suppressed epitestosterone production, while sill having “normal” testosterone levels? [Read more...]

Canadian Football League – Summer Camp for Violators of NFL Steroid Policy

The Canadian Football League (CFL) is the only professional sporting league in North America that has not yet implemented steroid testing for its football players. Former WADA chief Dick Pound had previously called the CFL a “summer camp” for NFL players suspended for violations of the NFL policy on anabolic steroids and related substances [Read more...]

Nanotechnology HGH Urine Testing at 2008 Growth Hormone Summit

The 2008 Growth Hormone Summit was held by the David Geffen School of Medicine at UCLA in conjunction with Major League Baseball (MLB) and the law firm of Foley and Lardner at the Beverly Hills Hotel in California on November 10, 2008. Dr. Gary Green, professor of family medicine at the UCLA medical school, chaired the conference of leading anti-doping experts and scholars. “Growth Hormone: Barriers to Implementation of hGH in Sports” addressed several scientific, legal and ethical issues involving testing athletes for human growth hormone (“Landmark conference to look at use of human growth hormone by athletes,” October 22). [Read more...]

Diuretic Bumetanide Used by NFL Players to Mask Anabolic Steroid Use?

Four of the eight NFL football players whose names were “leaked” as having violated the league’s policy on anabolic steroids and related substances were caught using the diuretic Bumex (bumetanide). New Orleans Saints running back Deuce McAllister and defensive ends Will Smith and Charles Grant tested positive for bumetanide as did Houston Texans deep snapper Bryan Pittman.

Reports of a “rash of positive steroid tests” in the NFL by news websites here and here and here and here are highly misleading and false since none of the players are alleged to have tested positive for steroids by the NFL. Nonetheless, MSNBC stated that one player tested positive for anabolic steroids with the headline “Report: Saints’ McAllister positive for steroids“, but deep in the article reported the truth that it was bumetanide. There are even plausible indications these may have involved inadvertent doping from weight loss supplements tainted with bumetanide.

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WADA Funds False Consensus Effect Study to Catch Dopers

The World Anti-Doping Agency (WADA) spends considerable money funding research aimed at catching athletes who use prohibited performance enhancing drugs (PEDs). WADA has always been on the losing end of an ongoing cat-and-mouse game. Anti-doping agencies are faced with several emerging doping methods such as synthetic blood doping, gene doping and designer steroids created via dynamic combinatorial chemistry (DCC).

A recently published study in the Journal of Occupational Medicine and Toxicology suggests that WADA has opened the door to social analysis and psychological profiling to catch steroids users and users of other banned substances. The WADA-funded researchers hope to establish a reliable indicator of self-reported use of performance-enhancing drugs.

The proposed anti-doping tool would ask the athlete various questions about their own self-reported doping, hypothetical doping scenarios, and the doping behavior of other athletes. If the athlete’s responses to the questionnaire fit the psychological profile of a doper, then this might represent evidence that athlete is doping even if the athlete does not admit to doping! The research is based on the False Consensus Effect from social psychology research.

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Infinite Number of Undetectable Designer Steroids with Combinatorial Chemistry

Researcher Jason Thomas, a graduate student in the doctoral program for synthetic organic chemistry at City University in New York, takes us inside the mind of a designer steroid chemist in an interview with Culturekiosque. Thomas describes a powerful tool that has the potential to create an infinite number of undetectable, designer anabolic steroids.

Once steroid designers specify the essential features and desired biological activity for steroid drug design, hundreds of novel designer steroids could be synthesized or simulated through Dynamic Combinatorial Chemistry (DCC) [Read more...]

Organized Doping in Greece Involving Anabolic Steroid Methyltrienolone

The Hellenic Olympic Committee (HOC) president believes organized doping is behind the fifteen Greek athletes who have failed anti-doping tests before and during the 2008 Beijing Olympics. Former 400-meter hurdles champion Fani Halkia, swimmer Ioannis Drymonakos, 400-meter runner Dimitrios Regas, sprinter Tassos Gousis and eleven unidentified Greek weightlifters all tested positive for the same prohibited anabolic steroid – methyltrienolone (“HOC president: Greek sports face organized doping,” August 18). [Read more...]

Anti-Doping Laboratory Equipment is Big Business at the 2008 Beijing Olympics

The China Anti-Doping Agency (CADA) spent approximately $10 million dollars and six years to create a new state of the art laboratory specifically for the 2008 Beijing Olympics. Roughly one quarter of that budget ($2.7 million) was used to purchase 60-80 various laboratory testing instruments. The primary beneficiaries of these purchases were the analytical laboratory equipment manufacturers Thermo Fisher Scientific, Agilent Technologies and Phenomenex (“Drugs at the Starting Line: The Olympics begin with new antidoping lab and measures to keep athletes honest,” August 11). [Read more...]

Dara Torres Takes Moral High Ground Despite Use of Performance Enhancing Drugs

Swimmer Dara Torres is an extraordinary athlete. The possibility that a 41-year old mother can compete alongside the best elite swimmers in the world with a legitimate chance at winning a gold medal at the 2008 Beijing Olympics is nothing short of phenomenal. There is nothing – no news or revelation – that could diminish her achievements in my eyes.

Having said that, I am disappointed to see Dara Torres publicly assert her moral superiority over other athletes who use performance enhancing drugs. Torres comes across as disingenous if not hypocritical when she decries the lack of a conscience in other competitors who use performance enhancing drugs.

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Cyclist Marta Bastianelli Uses Benfluorex Unaware of Similarities to Banned Substance

Italian cyclist Marta Bastianelli tested positive for a banned stimulant. She tested positive for the diet drug fenfluramine in a doping control conducted by the International Cycling Union (UCI) at the “Under-23 World Championships” in Verbania, Italy on July 5, 2008.

Bastianelli claims she never knowingly ingested a banned substance. She admitted to her obsession with weight control stating “I wanted to lose weight, like any girl.” She consulted with her doctor to find weight loss products that were not on the WADA banned substance list. Her doctor prescribed the drug Benfluorex. Benfluorex is an anti-diabetic drug that improves insulin sensitivity and glycemic control; as such it is often prescribed for weight loss. Benfluorex is not on the WADA banned substance list but it is structurally similar to Fenfluramine (which is listed) [Read more...]