September 25, 2020

Steroid Pharmacology

Articles related to the pharmacology of anabolic steroids or how steroids work

Masteron for Fat Loss

People on bodybuilding forums are always seeking a solution to facilitate fat loss. According to gymlore, some anabolic steroids have unique fat loss properties and should be used as the basis for a cutting steroid cycle. Is there any truth to this? Bill Roberts addresses the issue in his “Ask Bill Roberts” column on MESO-Rx specifically addressing whether Masteron is the best steroid for fat loss. [Read more…]

Sustanon 250 Steroid Profile by Bill Roberts

Bill Roberts recently wrote a new article profiling the anabolic steroid Sustanon 250 for MESO-Rx:

“Sustanon 250, whether as the trademarked Organon brand or as other products using the same name is one of the most popular testosterone ester products. Unlike most other steroid injectables, Sustanon comprises a mixture of esters: specifically, each ampule or mL contains testosterone propionate 30 mg, testosterone phenylpropionate 60 mg, testosterone isocaproate 60 mg, and testosterone decanoate 100 mg. This mixture includes short, medium, and long-acting esters.

“There are two advantages to combining multiple esters in the same formulation as Sustanon does…” [Read more…]

Hair Loss and Anabolic Steroids

Ask Bill Roberts: Will my hair loss increase when I take greater amounts of steroids? And if I only experience minor hair loss using large doses of anabolic steroids like winstrol, masteron and tren (steroids known for hair loss), would small doses of AAS known to cause minimal hair loss cause much if any at all? [Read more…]

Dianabol for Bridging Steroid Cycles

Ask Bill Roberts: Can Dianabol be used to bridge two different steroid cycles? Or does it prevent androgen receptors from cleaning out? Isn’t receptor downregulation a myth? [Read more…]

Infinite Number of Undetectable Designer Steroids with Combinatorial Chemistry

Researcher Jason Thomas, a graduate student in the doctoral program for synthetic organic chemistry at City University in New York, takes us inside the mind of a designer steroid chemist in an interview with Culturekiosque. Thomas describes a powerful tool that has the potential to create an infinite number of undetectable, designer anabolic steroids.

Once steroid designers specify the essential features and desired biological activity for steroid drug design, hundreds of novel designer steroids could be synthesized or simulated through Dynamic Combinatorial Chemistry (DCC) [Read more…]

Synergistic Effects of Growth Hormone with Performance Enhancing Drugs

Dr. Gary Gaffney from Steroid Nation posted an article on Huffington Post about the performance enhancing effects of human growth hormone. Gaffney responds to so-called experts who assert with certainty that growth hormone does not help performance in sports. As Lou Schuler stated in a recent post, the true effects of growth hormone on performance are not always empirically “knowable and measurable.”

Gaffney takes note of the lack of empirical research examining the performance enhancing effects of drugs that has historically resulted in mainstream medical organizations failing to recognize performance enhancing drugs. Given this along with results seen in “experiments of nature,” Gaffney feels it is reasonable to conclude that GH has performance enhancing effects:

[Read more…]

Difference Between Growth Hormone and Testosterone

Many people seem to assume that growth hormone and testosterone are both anabolic steroids. The media has shown very little interest in distinguishing the two throughout the entire war of steroids or the steroids in baseball fiasco. (Never mind the fact that there are dozens of different steroids with differing effects and side effects within the class of anabolic steroids.) When Sylvester Stallone tried to explain that growth hormone was a completely different class of drugs than anabolic steroids, he was met with widespread disbelief if not ridicule. Never mind the fact that he was correct.

So, I have to give credit to the few journalists who “try” to explain the difference between growth hormone and anabolic steroids like testosterone e.g. The Growth Hormone Myth: [Read more…]

Does Growth Hormone Speed Recovery and Improve Performance?

The debate over the performance-enhancing effects in baseball of growth hormone continues without a clear answer. Does growth hormone help recovery and healing from injury? Does growth hormone improve baseball performance? Various people have made the case that GH  does not help baseball players; others claim the drug helps improve performance dramatically.

Lou Schuler of Male Pattern Fitness has an excellent response to this question:

But the key here is to acknowledge that the only honest way to answer the question of the performance-enhancing effects of human growth hormone is to say, “We just don’t know.” [Read more…]