May 18, 2012

"Stupidity and Mistakes of the Anti-Doping Crusade"

Velo Vortmax blasts WADA for its resistance to change in the face of additional new evidence that the testosterone:epitestosterone ratio test is flawed (“Genetic variations in enzyme UGT2B17: Implications,” April 3).

WADA refuses to worry about trivial genetic factors. WADA is loath to do longitudinal tests of athletes. WADA might find a variable that might refute their laboratory findings or challenge their presumption of laboratory perfection. WADA would never invest time and money doing pedigree studies to determine if a single metabolite above threshold for exogenous testosterone is a trait common in a family, or among a group of people found in a geographical region. But idiosyncratic individual differences in medicine have been documented in many pedigree studies. For example, hematocrit levels above 50% have been found in fathers and sons of elite cyclists. These hematocirt levels are inherited tendencies, not based on EPO doping. The same is true for testosterone/epitestosterone ratio(s) and may be true for Carbon Isotope metabolite delta/delta scores.

[Read more...]

WADA Testing for Growth Hormone Within Weeks

According to  the New York Times, the World Anti-Doping Agency (WADA) has purchased thousands of doping kits that will be used to screen blood for exogenous human growth hormone (HGH). The top-secret HGH test has been available for some time but WADA only recently found a secret European-based manufacturer capable of producing significant quantities of the blood screening kits (“Agency will increase blood tests for HGH,” April 2).

WADA says the out of competition testing for HGH will begin within weeks The test will be used at the 2008 Beijing Olympics. Additionally, a WADA spokesperson says the the HGH screening kits will be used to analyze previously frozen blood samples from athletes. [Read more...]

Victor Conte BALCO Book Critical of Special Agent Jeff Novitsky

Victor Conte’s autobiographical account of the BALCO steroid scandal will hit bookstores in September 2008 (“BALCO founder Victor Conte has tell-all book ready,” March 30).

Slated for publication in September under the Skyhorse imprint, the book’s working title is “BALCO: The Straight Dope on Barry Bonds, Marion Jones and What We Can Do To Save Sports.” Conte, in conjunction with co-author Nathan Jendrick, promises to share “the dirt, the drugs, the doses, the names, dates and places, and a ‘prescription’ for a brighter future.”

He promises the “complete truth in its honest, unadulterated and raw form” and says he is “ready to tell the world everything.”

[Read more...]

Testosterone:Epitestosterone Ratio Test – False Negatives and False Positives

Source: Wikipedia

The scientific and anti-doping community continue to struggle with the development a test for exogenous growth hormone in athletes. They haven’t even been able to produce scientific evidence that growth hormone enhances athletic performance in spite of anecdotal evidence [from athletes and strength coaches] that this is the case.

But science continues to do a good job at finding weakness in the doping controls currently in place. Tip of the hat to Trust But Verify for alerting us of a new study which, among other things, tells us exactly how much exogenous testosterone some athletes can use and still pass the drug test.

The study reveals serious weaknesses in the testosterone:epitestosterone ratio test used by WADA and other anti-doping organizations (“Doping Test in Sports Confounded by Common Genetic Trait,” March 21). [Read more...]

Floyd Landis and Court of Arbitration for Sport

The Floyd Landis hearing before the Court of Arbitration for Sport (CAS) began today in Manhattan; for an excellent overview as usual see TBV. The five day appeal hearing is the last remedy in the appeal process for Floyd’s doping case involving positive testosterone test (“Landis, Stripped of Tour Title, Begins Final Appeal,” March 19).

Landis, 32, has spent millions of dollars on a defense that tried to cast doubt on the scientific validity of doping tests and the procedures followed at antidoping labs. But last September, in a 2-to-1 ruling, a United States Anti-Doping Agency arbitration panel concluded that Landis had used synthetic testosterone to achieve his comeback win at the 2006 Tour. As a result, he was barred from racing until January 2009….

In its 84-page ruling last year, the United States Anti-Doping Agency panel accepted Landis’s argument that the French antidoping lab that tested his urine samples from the Tour was sloppy in some of its operating procedures, and in how it documented its work. But the panel also found that a more sophisticated second test, conducted after the initial screening proved positive, was accurate.

But make no mistake about it, this isn’t just about Floyd Landis. It is also about the World Anti-Doping Agency (WADA), the anti-doping organization and program that is held as the model for drug testing around the world.

What Makes a Drug Performance Enhancing?

An article on the Psychology Today blog by Steven Kotler asked the question, “what makes a drug performance-enhancing?” It cites the WADA rules for banning performance enhancing drugs.

According to the World Anti-Doping Code, three substance categories govern the chemistry of cheating—1) It has the potential to enhance or enhances sport performance 2) It represents a potential or actual health risk 3) It is contrary to the spirit of sport—with a score of two-out-of-three being enough to earn a drug a place on the dreaded Prohibited List. [Read more...]

Dick Pound Nominated as President of Court of Arbitration of Sport

I find it hard to believe that the International Olympic Committee (IOC) has nominated the controversial Dick Pound as President of the Court of Arbitration of Sport (CAS). Pound, as the head of the World Anti-Doping Association (WADA), was widely criticized for his highly prejudiced and unethical abuse of the position. If Pound is elected President of the CAS… [Read more...]

Russian Anti-Doping Agency Turns to USADA

Russia has funded the new Russian Anti-Doping Agency (RusADA) with new equipment and $5 million. RusADA is an independent agency created to test athletes for anabolic steroids and other performance-enhancing drugs. Representatives from RusADA are visiting the United States to learn more about the U.S. doping control program – United States Anti-Doping Agency (USADA) – and strengthen relationships with their U.S. counterparts. [Read more...]

World Anti-Doping Association Allows Surgically Enhanced Performance

Several observers, including myself, have wondered why surgical procedures such as LASIK laser eye surgery or ulnar collateral ligament reconstruction (better known as Tommy Johns surgery) are not considered cheating. After all, they could arguably offer a greater advantage than anabolic steroids. If steroids are considered cheating, why aren’t these surgical procedures?

The answer is quite simple. It is not against the rules. The World Anti-Doping Association (WADA) has no prohibitions whatsoever on performance enhancement surgeries. They are all permitted. [Read more...]

Abscess from Anabolic Steroid Injections or B12?

ESPN reports that trainer Brian McNamee claims Roger Clemens developed an abscess in his buttock resulting from injections of anabolic steroids in 1998. No medical records have surfaced to corroborate this claim. Of course, if Roger Clemens claims that he regularly received intramuscular injections of B-12, then this could have been equally responsible for the alleged abscess. However, Clemens’ attorney has denied that Roger Clemens’ had an abscess.

But ESPN found an “anti-doping expert” who claims that anabolic steroid injections represent a special type of intramuscular injection that is more likely to cause abscesses. According to Gary Wadler of the World Anti-Doping Agency (WADA). [Read more...]